Friday, December 1, 2017

U.S. Opioids Market to Surpass US$ 18,985.4 Million Threshold by 2024

U.S. Opioids Market, By Drugs (Codeine, Fentanyl, Meperidine, Methadone, Morphine, and Hydrocodone) and Therapeutic Application (Pain Management (Neuropathic Pain, Migraine, Back Pain, Osteoarthritis Pain, Cancer Pain, and Others), Cough Treatment, and Diarrhea Treatment) was valued at US$ 12,627.6 million in 2016 and is expected to exhibit CAGR of 5.2% over the forecast period (2016–2024), as highlighted in a new report published by Coherent Market Insights. Increasing incidences of chronic diseases, such as cancer and cardiovascular diseases in developed countries such as U.S., easy accessibility and low cost of opioids pain killers compared to other pain killers such as nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen are the major drivers for growth of the U.S. opioids market. Strict regulatory guidelines for opioids prescription and increasing awareness about harmful effects of the drug are restraining growth of the market.  


In October 2017, Government of the U.S. declared the opioid crisis, as a public health emergency. This declaration is expected to increase the awareness about the drug overuse or abuse and it led the doctors to reduce from over-prescribing the opioids drug. Moreover, Attorney General of more than 35 states sent a letter to the America’s Health Insurance Plans, national association whose members provide coverage for health care and related services, urging its members to reconsider coverage policies that may be fueling the growth of opioid crisis. Due to low cost of opioids compared with other painkillers such as nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen, the insurance company has covered the opioid but not costly one which resulted in limited access to costly painkillers. This is the major concern for all states and letter from Attorney general of the states have been sent to modify this coverage policy so that every painkiller have equal access. 
Due to increased focus on opioids drug, leading pharmacy chains such as CVS has also opted to cooperate the government in managing this crisis. CVS health has announced to reduce opioid prescription and has given detailed guidelines for its use. One among such steps is that their chemist are expected to contact doctors in case of is over prescription of drug.
Browse 11 Market Data Tables and 19 Figures spread through 132 Pages and in-depth TOC on U.S. Opioids Market by Drugs (Codeine, Fentanyl, Meperidine, Methadone, Morphine and Hydrocodone) and Therapeutic Application (Pain Management (Neuropathic Pain, Migraine, Back Pain, Osteoarthritis Pain, Cancer Pain, Others), Cough Treatment and Diarrhea Treatment)
To know the latest trends and insights prevalent in the U.S. Opioids Market, click the link below:
According to the National Center for Health Statistics (NCHS), a division of the Centers for Disease Control and Prevention, (CDC) in 2017, drug overdose killed around 64,070 people in the U.S. in 2016, a rise of 21% over the 52,898 drug overdose deaths was recorded in 2015 and death due to synthetic-opioid fatalities more than doubling in number during the same time increasing from 9,945 in 2015 -2016 to 20,145 in 2016 - 2017.
The same source estimated that opioid overdose resulted in the deaths of approximately 300,000 people in the U.S. during 1999 – 2015. The CDC figure also shows that the rate of increase in deaths from synthetic opioid was much higher than natural or semi-synthetic opioids during 1999 - 2015. According to the CDC report, 2016 nearly half of all opioid overdose deaths involved a prescription opioid.
Key Takeaways of the U.S. Opioids Market:
  • The U.S. Opioids market is expected to exhibit a CAGR of 5.2% over the forecast period (2017 – 2025), owing to the increasing incidences of chronic pain, especially in emerging economies.
  • Opioids overuse or abuse, which is contributing significantly to this market expansion has become the major concern in the economy.
  • Alternative drugs like cannabis has gained attraction in recent times for pain management. If proven effective and safe, cannabis has potential to replace the opioids.
  • The use of medical cannabis has been endorsed by numerous professional organizations in the U.S. including the American Academy of Family Physicians (AAFP), the American Public Health Association (APHA), and the American Nurses Association (ANA).
  • Pressure is mounting on leading pharmacy chain, such as CVS to act positively to limit the opioid drug prescription.
  • Key companies covered in the global U.S. opioids market report include Purdue Pharma L.P., Titan Pharmaceuticals, Inc., Boehringer Ingelheim GmbH, Janssen Pharmaceuticals, Inc., Sanofi S.A., Sun Pharmaceuticals Industries Limited, Mallinckrodt Pharmaceuticals, Egalet Corporation, Endo Pharmaceuticals plc, Allergan, Plc., and Pfizer Inc.
About Coherent Market Insights:
Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.
Contact Us:
Mr. Shah
Coherent Market Insights
1001 4th Ave,
#3200
Seattle, WA 98154
Tel: +1-206-701-6702
Email: sales@coherentmarketinsights.com
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Bone Replacement Products Market to Surpass US$ 46.6 Billion Threshold by 2025

The Global Bone Replacement Products Market, by Product Type (Hip Replacement, Knee Replacement, Trauma and Extremities, and Spine Replacement), by Material (Metals, Ceramics, Plastics, and Combination of Materials), by End User (Hospitals, Orthopedic Clinics, and Ambulatory Surgical Centers), and by Region (North America, Latin America, Europe, Asia Pacific, the Middle East, and Africa) was valued at US$ 31.7 billion in 2016 and is projected to exhibit a CAGR of 4.4% over the forecast period (2017 – 2025), as highlighted in a new report published by Coherent Market Insights. The development of patient-specific hip implants considering the anatomic individuality or extremely difficult reconstructive cases of patients is a major factor propelling the demand for hip replacement products. For instance, Zimmer Biomet’s patient-matched implant (PMI) department works directly with surgeons to address the most severe cases of bone loss or deformity.


Growing preference for minimally invasive procedures to propel growth of market
Minimally invasive and small incision replacement surgery is an evolving area with improved rehabilitation and pain management to accelerate post-surgery recovery. Increasing adoption of minimally invasive techniques by professionals, owing to long-term benefits is expected to propel growth of the bone replacement products market. Moreover, benefits of minimally invasive replacement procedure have been reported to include less damage to soft tissues, leading to a quick and less painful recovery.
Rising number of bone tumors and trauma cases is expected to accelerate the demand for bone replacement products
Treatment of bone cancers with surgical procedures involves replacement of cancerous bone by bone replacement products or implants. Thus, increasing incidence of bone cancers such as osteosarcoma, chondrosarcoma, and Ewing’s sarcoma, which require bone replacement, is in turn expected to propel growth of the bone replacement products market. According to the American Society of Clinical Oncology, 2014, bone sarcomas account for 0.2% of all malignancies globally with the incidence rate for bone and joint malignancies to be 0.9 per 100,000 people annually, in the U.S. Furthermore, increasing cases of bone fracture trauma due to fall, motor vehicle accident or sports, require medical intervention (orthopedics) thus, augmenting the demand for bone replacement products. According to the National Trauma Institute, in 2014, traumatic injury is the major cause of death globally with the major share of road injury (29.1%) and falls (11.6%).
Browse 45 Market Data Tables and 40 Figures spread through 230 Pages and in-depth TOC on “Bone Replacement Products Market”- Global Forecast to 2025
To know the latest trends and insights prevalent in the bone replacement products market, click the link below:
The market players are engaged in strategic acquisitions and collaborations to increase the portfolio diversification and to introduce exciting new platform technologies. For instance, in 2015, United Orthopedic Corporation collaborated with Shinva Medical Instrument Co., Ltd and New China Life Health Co., Ltd. to expand the sales of bone replacement products in China. Furthermore, in 2016, Zimmer acquired LDR Holding Corporation to enhance innovation and growth of their spine segment. The production of innovative products with research and development activities is expected to enhance the competitive environment among the manufacturers. For instance, in 2015, B. Braun Melsungen AG launched a new 7-layer advanced surface technology with zirconium nitride coated on knee implant to improve its mechanical properties and biocompatibility, thus reducing wear rate by 65%.
Key Takeaways of the Bone Replacement Products Market:
  • The global bone replacement products market is expected to exhibit a CAGR of 4.4% over the forecast period, owing to the presence of high potential market especially in Asia Pacific, Latin America, the Middle East, and Africa
  • Among materials, the combination of materials segment holds a dominant position in the market, as these material implants have enhanced wear resistant and biocompatible properties as compared to the other materials
  • Among end user, the ambulatory surgical centers segment is expected to hold a dominant position in the bone replacement products market, owing to the minimal requirement of prolonged postoperative monitoring and hospital stay
Some of the major players operating in the global bone replacement products market are Zimmer Biomet Holdings, Inc., B. Braun Melsungen AG, Stryker Corporation, Smith & Nephew Plc, United Orthopedic Corporation, Depuy Synthes, Medtronic Plc., Japan Medical Dynamic Marketing, Inc., JRI Orthopedics, Exactech, Inc., and Mathys.
About Coherent Market Insights:
Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.
Contact Us:
Mr. Shah
Coherent Market Insights
1001 4th Ave,
#3200
Seattle, WA 98154
Tel: +1-206-701-6702
Email: sales@coherentmarketinsights.com
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Bone Graft and Substitutes Market to surpass well beyond US$ 4,235.7 Mn by 2025

The Global Bone Graft and Substitutes Market, by Product Type (Bone Grafts and Bone Graft Substitutes), by Application (Spinal Fusion, Dental Bone Grafts, Craniomaxillofacial, Joint Reconstruction, Trauma and Extremities), and by Region (North America, Latin America, Europe, Asia Pacific, the Middle East, and Africa) was valued at US$ 2,640.1 Mn in 2016 and is projected to exhibit a CAGR of 5.5% over the forecast period (2017 – 2025), as highlighted in a new report published by Coherent Market Insights. Rise in number of reconstructive joint surgeries coupled with development of novel bone grafting substitutes are major factors expected to drive growth of the global bone graft and substitutes market over the forecast period.


Number of hip and knee reconstructive joint surgeries are increasing globally due to growing aging population as well as increasing adoption of sedentary lifestyle. According to Canadian Institute of Health Information, the number of knee replacement surgeries increased by 20.3% in Canada from 2009-2010 to 2014-2015. Bone grafts and substitutes are used in order to fill the voids and damages caused in the knees and hips, thereby healing the broken sites through natural growth. These techniques use various advanced machines and equipment for precision, accuracy, and ease. This has led to increase in the success rate of bone graft surgeries, in turn, propelling growth of the market.
Additionally, rise in medical tourism, especially in the developing economies such as Brazil, Belgium, India, China, Hong Kong are also responsible for driving growth of the global bone grafts and substitutes market. Bone grafting procedures performed in these countries are cost-effective, which in turn, drives traction from the populace living in the developed countries where the prices for these procedures are relatively more expensive. Besides cost-savings, surgeries performed in medical tourism countries offer equivalent levels of quality as well as luxurious post-operative care. This helps boost the market for bone graft and substitutes, specifically in  Latin America and Asia Pacific.
Browse 35 Market Data Tables and 30 Figures spread through 287 Pages and in-depth TOC on “Bone Graft and Substitutes Market”- Global Forecast to 2025
To know the latest trends and insights prevalent in the bone graft and substitutes market, click the link below:
Manufacturers are focusing on developing a variety of synthetic bone graft substitutes and derivatives of allografts such as demineralized bone matrix for better results, high performance, and easy accessibility of synthetic compounds. Synthetic enhanced grafts that help in the improvement of the quality of post-surgical recovery are attracting large customer base, majorly owing to the cost effectiveness and reliability offered by these grafts. For instance, i-Factor by Cerapedics is a peptide enhanced graft that is used in cervical discectomy and fusion surgeries. The graft helps to support bone growth through cell attachment and aviation. Moreover, IBI S.A. developed a bone graft named SmartBone through advanced tissue engineering technologies with resorbable polymers and cell nutrients to enable quick and efficient osteoconduction with a well-blended integration.
Key Takeaways of the Bone Graft and Substitutes Market:
  • The global bone graft and substitutes market is expected to exhibit a CAGR of 5% over the forecast period, owing to the presence of potential market especially in Asia Pacific, and Latin America.
  • Among bone grafts, the autografts segment holds a dominant position in the market, as it is the most established procedure in the grafting sector, followed by allografts. The segment is gaining traction due to high availability and ability to suffice almost all the requirements of an ideal bone graft.
  • Among applications, the spinal fusion segment holds a dominant position in the market, owing to significant rise in the number of spinal procedures carried out across the globe
  • Some major players operating in the global bone graft and substitutes market are Ace Surgical Supply Co., Inc., NovaBone Product LLC, Medtronic Plc, Stryker Corporation, Zimmer Biomet Holdings, Inc., BioHorizons Implant Systems, Inc., Novadip Biosciences, Orthofix International N.V., Globus Medical, Inc., and Bone Therapeutics SA.
About Coherent Market Insights:
Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.
Contact Us:
Mr. Shah
Coherent Market Insights
1001 4th Ave,
#3200
Seattle, WA 98154
Tel: +1-206-701-6702
Email: sales@coherentmarketinsights.com
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